2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131479
    Threo-dihydrobupropion hydrochloride
    		99.00%
    Threo-dihydrobupropion hydrochloride is a primary metabolite of Bupropion. Threo-dihydrobupropion hydrochloride can be used for the research of the depression, behavioral, and biochemistry.
    Threo-dihydrobupropion hydrochloride
  • HY-133794
    Dasatinib N-oxide
    		99.24%
    Dasatinib N-oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src/Bcr-Abl inhibitor.
    Dasatinib N-oxide
  • HY-131280
    Devaleryl Valsartan Impurity
    		99.98%
    Devaleryl Valsartan Impurity is an intermediate in the synthesis of Valsartan.
    Devaleryl Valsartan Impurity
  • HY-113018A
    (S)-Ibuprofen acyl-β-D-glucuronide
    		98.47%
    (S)-Ibuprofen acyl-β-D-glucuronide ((S)-Ibuprofen glucuronide) is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, a non-steroidal anti-inflammatory drug. (S)-Ibuprofen acyl-β-D-glucuronide is an acylglucuronic acid metabolite produced by S-ibuprofen in the liver.
    (S)-Ibuprofen acyl-β-D-glucuronide
  • HY-126857
    5-Hydroxyomeprazole
    5-Hydroxyomeprazole is the major metabolite of Omeprazole (HY-B0113).
    5-Hydroxyomeprazole
  • HY-107856R
    5-Fluorouridine (Standard)
    5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of5-Fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis.
    5-Fluorouridine (Standard)
  • HY-137215
    4'-trans-Hydroxy Cilostazol
    4'-trans-Hydroxy Cilostazol is a metabolite of Cilostazol.
    4'-trans-Hydroxy Cilostazol
  • HY-G0001A
    Lurasidone Metabolite 14283 hydrochloride
    		99.06%
    Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone. Lurasidone is a FDA approved agent for the treatment of schizophrenia.
    Lurasidone Metabolite 14283 hydrochloride
  • HY-118099
    Florfenicol amine hydrochloride
    		98.61%
    Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine hydrochloride
  • HY-77734
    AR-C133913XX
    		99.76%
    AR-C124910XX is a metabolite of Ticagrelor (HY-10064 ). Ticagrelor is a reversible oral P2Y12 receptor antagonist, and can be used for study of platelet aggregation.
    AR-C133913XX
  • HY-136591
    Demoxepam
    		98.39%
    Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects. Demoxepam has an inhibitory effect on in vitro [3H]tryptophan binding to rat hepatic nuclei.
    Demoxepam
  • HY-130239
    14(S)-HDHA
    		98.0%
    14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway.
    14(S)-HDHA
  • HY-N6683
    15-Acetyl-deoxynivalenol
    		99.82%
    15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells.
    15-Acetyl-deoxynivalenol
  • HY-B1348
    Dimethadione
    		99.93%
    Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal.
    Dimethadione
  • HY-135325
    4-Hydroxyacetophenone oxime
    		99.96%
    4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent.
    4-Hydroxyacetophenone oxime
  • HY-W354479
    6-Thioinosine Phosphate
    6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug.
    6-Thioinosine Phosphate
  • HY-131466
    N-Methyl Palbociclib
    		99.94%
    N-Methyl Palbociclib is an impurity of Palbociclib (HY-50767). Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor.
    N-Methyl Palbociclib
  • HY-B2150
    4-Hydroxyantipyrine
    		99.9%
    4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain.
    4-Hydroxyantipyrine
  • HY-127118
    Pteropterin
    		99.31%
    Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity.
    Pteropterin
  • HY-W357818
    Glycinexylidide
    Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease.
    Glycinexylidide
Cat. No. Product Name / Synonyms Application Reactivity